The 2021 NFL regular-season schedule will be released next Wednesday, May 12th and while the Buffalo Bills know who they will play, the time and dates are yet to be determined.

The NFL schedule release has become one of the best dates on the calendar for Bills fans. Trying to predict who they will play and where. Some fans have preferences.

For instance, I think most fans want to open up at home and it's always cool when you have a few primetime games. The Bills got that in 2020. They played Kansas City, Pittsburgh, Tennesee, San Fransisco, and New England in primetime and it's safe to assume we'll get more of that in 2021.

In case you're wondering, here are the Bills opponents for 2021, and don't forget, they play 17 games this season (not 16):


  • Miami Dolphins
  • New York Jets
  • New England Patriots
  • Atlanta Falcons
  • Carolina Panthers
  • Houston Texans
  • Indianapolis Colts
  • Pittsburgh Steelers
  • The Washington Football Team


  • Miami Dolphins
  • New York Jets
  • New England Patriots
  • Jacksonville Jaguars
  • New Orleans Saints
  • Tampa Bay Buccaneers
  • Tennessee Titans
  • Kansas City Chiefs

Now, what date and times would you like to see for those opponents? We got a feeling Bills fans are itching to see these matchups. Here are the top five matchups Bills fans want to see for 2021.

The Top 5 Games Bills Fans Want In 2021

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